The advancements in machine learning, when combined with the vast datasets of whole genomes, enable the creation of biological foundational models. Evo is a genomic foundational model that, after training, can generate DNA sequences on a whole-genome scale, surpassing single molecules and short sequences. It can design synthetic multi-component biological systems. On a whole-genome scale, Evo can predict essential genes in bacteria or phages without any supervision.
7 Billion Parameter Training: A New Benchmark for General Biological Models from DNA, RNA, Proteins to the Whole Genome
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