Recently, an interdisciplinary research team from the Technical University of Munich, the Helmholtz Zentrum Munich, and ETH Zurich published an important study introducing an innovative framework called Moscot (Multi-Omics Single-Cell Optimal Transport), which successfully reconstructed the developmental trajectories of 1.7 million mouse embryonic cells at 20 time points. This study, published in the journal Nature, marks a significant breakthrough in the field of single-cell genomics. The design inspiration for the Moscot framework comes from the optimal transport theory of the 18th century.