The latest version of AlphaFold released by DeepMind has achieved a significant improvement in the accuracy of protein structure prediction, with an increase of nearly 10%. This technology has also expanded the scope of predictions to include RNA structures and the prediction capabilities of other biomolecular structures. The new generation of AlphaFold is not limited to predicting protein structures; it also includes the prediction of structures of biological molecules such as nucleic acids and small molecule ligands, and even handles complex biological processes such as residue modifications. This breakthrough not only propels the development of the biomedical field but also enhances the scientific understanding of the molecular mechanisms that constitute the human body and the natural world. The performance improvement of AlphaFold provides scientists with more powerful tools, accelerating the pace of scientific exploration. The release of the new generation of AlphaFold marks the beginning of the digital biology era, which will bring revolutionary changes to biomedical research, drug design, and scientific exploration.