AlphaMissense

Predicts the functional impacts of all possible human amino acid substitutions and missense mutations

CommonProductOthersDeep LearningDevelopment Programming

AlphaMissense is an open-source protein variant effect prediction model that predicts theFunctional impact of all possible human amino acid substitutions. It employs deep learning to predict at the protein sequence level without requiring experimental structural information. AlphaMissense can accurately predict the functional impacts of pathogenic variants that have been verified by cell experiments, which is significant for drug design and the study of genetic diseases.

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