PathChat 2 is the latest multimodal generative AI model released by Modella AI, designed specifically for pathologists, students, and researchers. It can reason about pathological images and text, serving as a valuable tool for research and education. Compared to its predecessor, PathChat 1, PathChat 2 demonstrates significant performance improvements in diagnostic identification, morphological description, instruction following, and the execution of diverse tasks such as open-ended question answering and report summarization.