CyberHost is an end-to-end audio-driven human animation framework that employs a region codebook attention mechanism to generate complete hand integrity, identity consistency, and natural movement. The model utilizes a dual U-Net architecture as its foundational structure and implements motion frame strategies for temporal continuity, establishing a baseline for audio-driven human animation. CyberHost enhances the quality of synthesized results through a series of human-centered training strategies, including body movement maps, hand clarity scoring, reference features for pose alignment, and local enhancement supervision. It is the first audio-driven human diffusion model capable of zero-shot video generation within the human domain.