Make-Your-Anchor is a 2D virtual avatar generation framework based on diffusion models. It can automatically generate anchor-style videos with precise upper body and hand movements from just about 1 minute of video footage. The system employs a structure-guided diffusion model to render 3D mesh states into character appearances. Through a two-stage training strategy, it effectively binds movement with specific appearances. To generate videos of arbitrary length, the frame-wise diffusion model's 2D U-Net is extended to 3D form, and a simple and effective batch overlapping temporal denoising module is proposed, breaking through the video length limit during inference. Finally, a face enhancement module based on specific identities is introduced to improve the visual quality of the facial area in the output video. Experiments show that the system outperforms existing techniques in visual quality, temporal consistency, and identity faithfulness.